AML1-ETO IN Acute Myeloid Leukemia Back Order Form Order Form

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    About this biomarker


    Among the most frequent genomic lesions in Acute Myeloid Leukemia (AML) are the
    reciprocal translocation t(8;21)(q22q22) and the pericentric inversion of chromosome 16, inv(16)(p13q22).

    The corresponding leukemia specific fusion transcripts are respectively AML1-ETO and CBFß-MYH11, detected in about 2-12% and 1-5% respectively of AML cases and associated with favorable prognosis.

    These two specific fusion transcripts can be detected by polymerase chain reaction
    (PCR) based methods at diagnosis, and are used to quantify minimal residual disease (MRD).

    See relevant publications

    Why choose our products

    Ipsogen FusionQuant® kits are unique molecular kits providing standardization and accurate quantification of fusion gene transcripts in leukemia.

    FusionQuant® kit key points

    • Sensitive and quantitative measurement of the fusion transcript
    • Determination of the expression level of the fusion transcript relative to the ABL, GUS or BCR control genes
    • Facilities and QMS compliant with ISO 13485 : 2003
    • Multi-instrument compatibility
    • Ready to use pre-diluted solutions
    • Reduced risk of contamination
    • Validated standards for the specific fusion and control gene
    • EAC Standardized RQ-PCR procedures

    Our Products (RUO products)

      Main Products
    Biomarker Product Indication(s) Content Product description Instructions for use Material Safety Data Sheet Product reference Add to basket
    AML1-ETO FusionQuant®Kit Monitoring
    		 24-30 samples in duplicate  PD_AML1-ETO&CBFb-MYH11tA_FusionQuant kit_RUO  IFU_FQ_kit_RUO  MSDS_FQPP_RUO FDS_FQPP_RUO FQPP-01
      Associated Products
    Biomarker Product Indication(s) Content Product description Instructions for use Material Safety Data Sheet Product reference Add to basket
    RT complete set Reverse Transcription Kit Monitoring
    		 33 reactions  IFU reverse transcription kit  MSDS_Kit_RT FDS_kit_RT RT-01
    AML1-ETO Fusion Gene Standard FusionQuant® Standards Monitoring
    		 4 reactions in duplicate  PD_Fusion Quant standards  IFU_FQ_Standards_RUO  MSDS_CGRS&FGRS FDS_CGRS&FGRS FGRS-01
    ABL Control Gene FusionQuant® CG Standards 4 reactions in duplicate  PD_Fusion Quant standards  IFU_FQ_Standards_RUO  MSDS_CGRS&FGRS FDS_CGRS&FGRS CGRS-01
    B2M Control Gene FusionQuant® CG Standards 4 reactions in duplicate  PD_Fusion Quant standards  IFU_FQ_Standards_RUO  MSDS_CGRS&FGRS FDS_CGRS&FGRS CGRS-02
    GUS Control Gene FusionQuant® CG Standards 4 reactions in duplicate  PD_Fusion Quant standards  IFU_FQ_Standards_RUO  MSDS_CGRS&FGRS FDS_CGRS&FGRS CGRS-03
    TBP Control Gene FusionQuant® CG Standards 4 reactions in duplicate  PD_Fusion Quant standards  IFU_FQ_Standards_RUO  MSDS_CGRS&FGRS FDS_CGRS&FGRS CGRS-04
    BCR Control Gene FusionQuant® CG Standards 4 reactions in duplicate  PD_Fusion Quant standards  IFU_FQ_Standards_RUO  MSDS_CGRS&FGRS FDS_CGRS&FGRS CGRS-05