CLLU1 IN Chronic Lymphocytic Leukemia Back Order Form Order Form

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    About this biomarker


    CLLU1 gene (CLL Upregulated gene 1) is the first disease specific gene identified in CLL.

    The gene was mapped on chromosome 12q22.

    Both pilot and larger independent studies have shown that CLLU1 overexpression was significantly associated with shorter overall survival and serves as strong prognostic indicator in patients younger than 70 years.

    CLLU1 expression added further prognostic information within all prognostic subgroups, including FISH analyses, IgVH mutational status, CD38 and ZAP-70 expression, with the exception of unmutated IgVH.

    Unlike CD38 and ZAP-70, CLLU1 is exclusively expressed in CLL cells, cell purification is therefore not needed to quantify CLLU1 expression.

    See relevant publications

    Why choose our products

    Ipsogen ProfileQuant® kits are unique quantitative molecular kits aiming at standardizing, detecting and quantifying profile gene transcripts in human cells.

    ProfileQuant® Kit key points

    Laboratory advantages

    • Use peripheral blood specimen
    • Quick test less than 3-hour turn-around time
    • Sensitive quantitative measurement of the gene transcript

    Description & performances
    • 24 to 30 patient samples in duplicate
    • Results in normalized copy numbers (NCN)
    • Facilities and QMS compliant with ISO 13485 : 2003
    • Multiplatform compatibility
    • Standardized RQ-PCR procedures

    Our Products (RUO products)

      Main Products
    Biomarker Product Indication(s) Content Product description Instructions for use Material Safety Data Sheet Product reference Add to basket
    CLLU1 ProfileQuant® Kit Prognosis
    		 24-30 samples in duplicate  PD_CLLU1_PQ_kits_RUO  IFU_PQ_CLLU1_RUO  MSDS_PQPP-02_03_04 FDS_PQPP-03_04 PQPP-04