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Reciprocal rearrangements of the MLL gene are among the most common chromosomal abnormalities in both Acute Lymphoblastic and Myeloid Leukemia.
The MLL gene, located on the 11q23 chromosomal band, is involved in a large number of different chromosomal translocations resulting in a range of MLL fusion proteins.
These different types of translocations tend to be associated with a specific type of leukemia.
For example, the t(9;11) translocation of the MLL and AF9 genes is mainly found in acute myeloid leukemia while the t(11;4) translocation of the MLL and AF4 genes is found in Acute lymphoblastic leukemia.

See relevant publications

Main Products
Biomarker	Product	Indication(s)	Content	Product description	Instructions for use	Material Safety Data Sheet	Product reference	Add to basket
MLL-AF9 type A Fusion Gene Standard	FusionQuant® Standards	Monitoring	4 reactions in duplicate				FGRS-16
MLL-AF9 type B Fusion Gene Standard	FusionQuant® Standards	Monitoring	4 reactions in duplicate				FGRS-17
MLL-AF6 Fusion Gene Standard	FusionQuant® Standards	Monitoring	4 reactions in duplicate				FGRS-18
MLL-DUP Fusion Gene Standard	FusionQuant® Standards	Monitoring	4 reactions in duplicate				FGRS-19
MLL-ENL e9e2 Fusion Gene Standard	FusionQuant® Standards	Monitoring	4 reactions in duplicate				FGRS-20
MLL-ENL e10e2 Fusion Gene Standard	FusionQuant® Standards	Monitoring	4 reactions in duplicate				FGRS-21
MLL-AF9 e8e10 Fusion Gene Standard	FusionQuant® Standards	Monitoring	4 reactions in duplicate				FGRS-23
MLL-ELL e9e2 Fusion Gene Standard	FusionQuant® Standards	Monitoring	4 reactions in duplicate				FGRS-24
MLL-ELL e8e2 Fusion Gene Standard	FusionQuant® Standards	Monitoring	4 reactions in duplicate				FGRS-25
MLL-AF1p e10e2 Fusion Gene Standard	FusionQuant® Standards	Monitoring	4 reactions in duplicate				FGRS-26
Associated Products
Biomarker	Product	Indication(s)	Content	Product description	Instructions for use	Material Safety Data Sheet	Product reference	Add to basket
ABL Control Gene	FusionQuant® CG Standards		4 reactions in duplicate				CGRS-01
B2M Control Gene	FusionQuant® CG Standards		4 reactions in duplicate				CGRS-02
GUS Control Gene	FusionQuant® CG Standards		4 reactions in duplicate				CGRS-03
TBP Control Gene	FusionQuant® CG Standards		4 reactions in duplicate				CGRS-04
BCR Control Gene	FusionQuant® CG Standards		4 reactions in duplicate				CGRS-05